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Study: Experimental Hep C Treatment May Cure 97% Of Liver Transplant Patients.
Bloomberg News (11/11, Chen) reports that in a
“mid-stage study of 34 patients, 33 [97%] were cured of the virus after 24
weeks of treatment” using AbbVie Inc. (ABBV)’s hepatitis C treatment, an
“experimental cocktail of ombitasvir, ritonavir, dasabuvir, ABT-450, and ribavirin,
an antiviral drug used to supplement hepatitis C treatments.” The study,
published today in the New England Journal of Medicine, involved patients “who
had received a liver transplant.”
Reuters (11/11, Penumudi) reported that in a
study involving genotype 4 hepatitis C patients, the treatment was effective
100% of the time.
Gilead: Hepatitis C Combination Treatment Cures 96-97% Of
Cirrhosis Patients. Reuters (11/12, Pierson) reports that Gilead
Sciences Inc. announced that its new combination hepatitis C drug Harvoni
(ledipasvir/sofosbuvir), which was approved by the US FDA last month, cured
96-97% of cirrhosis patients with the genotype 1 of the virus who had failed to
benefit from other treatments. In one subset of the 155 patients involved in
the study, the patients took Harvoni alone for 24 weeks and were cured at a
rate of 97%. In a group of patients who received Harvoni plus ribavirin for 12
weeks, the cure rate was 96%.
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